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Sang Hyuk Lee 1 Article
Extranodal Follicular Dendritic Cell Sarcoma with Rapid Growth in Parapharynx: A Case Report
Jung-Soo Pyo, Guhyun Kang, Sung-Im Do, Seoung Wan Chae, Kyungeun Kim, Sang Hyuk Lee, Yoon-La Choi, Joon Hyuk Choi, Jin Hee Sohn, Dong-Hoon Kim
Korean J Pathol. 2012;46(3):306-310.   Published online June 22, 2012
DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.3.306
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AbstractAbstract PDF

Follicular dendritic cell sarcoma (FDCS) is a rare malignancy arising from the antigen-presenting cells in the lymph node and extranodal tissue. We describe a 31-year-old male patient who presented with a swelling of the left parapharynx. The radiologic findings showed a 4.7×4.5×1.9 cm-sized, ill-defined mass in the left parapharyngeal space. A fine-needle aspiration cytology was performed and it showed scattered, irregular, cohesive clusters of tumor cells with a spindle-to-ovoid shape with irregular contours in a background of lymphocytes. Based on these findings, a diagnosis of spindle cell neoplasm was made. The surgically resected tumor was composed of elongated, ovoid or polygonal cells showing positive immunohistochemistry for CD21, CD23, and CD35. Postoperatively, the residual tumor was observed to undergo a rapidly growth. There is an overlap in the cytologic and histologic findings between FDCS of the parapharynx and other tumors. Pathologists should therefore be aware of its characteristics not only to provide an accurate diagnosis but also to recommend the appropriate clinical management.

Citations

Citations to this article as recorded by  
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    RUI-FEN WANG, WEI HAN, LEI QI, LI-HUI SHAN, ZHENG-CAI WANG, LI-FENG WANG
    Oncology Letters.2015; 9(1): 391.     CrossRef
  • Follicular Dendritic Cell Sarcoma of Parapharyngeal Space: A Case Report and Review of the Literature
    Turki Al-Hussain, Muhammad Saleem, Suresh Babu Velagapudi, Mohammad Anas Dababo
    Head and Neck Pathology.2015; 9(1): 135.     CrossRef
  • Clinical and pathological features of head and neck follicular dendritic cell sarcoma
    Ji Li, Min-Li Zhou, Shui-Hong Zhou
    Hematology.2015; 20(10): 571.     CrossRef

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